Etanercept‐Methotrexate Combination Therapy Initiators Have Greater Adherence and Persistence Than Triple Therapy Initiators With Rheumatoid Arthritis
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چکیده
منابع مشابه
Etanercept‐Methotrexate Combination Therapy Initiators Have Greater Adherence and Persistence Than Triple Therapy Initiators With Rheumatoid Arthritis
OBJECTIVE To estimate adherence and persistence with etanercept plus methotrexate (ETN-MTX) combination therapy and MTX, hydroxychloroquine, and sulfasalazine triple therapy at 1 year following treatment initiation in adults with rheumatoid arthritis (RA). METHODS This retrospective analysis used data from the Truven Health MarketScan Commercial and Medicare Supplemental databases from Januar...
متن کاملCombination therapy in rheumatoid arthritis.
It has become clear that early suppression of rheumatoid arthritis disease activity is important in preventing progressive joint destruction and functional decline. To achieve this goal, many rheumatologists today advocate a more aggressive approach, using combinations of classic disease-modifying antirheumatic drugs-often including methotrexate-or new drugs. During the last 2 years, the combin...
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The role of combination therapy in rheumatoid arthritis (RA) is increasing with the development of new treatment modalities. Past combinations of slow-acting anti-rheumatic drugs resulted in either excessive side-effects or lack of efficacy over single-agent therapy. However, refined methodology and a better understanding of the mechanism of action of newer agents have led to improved combinati...
متن کاملAdherence to Methotrexate therapy in Rheumatoid Arthritis
OBJECTIVE To determine adherence to methotrexate (MTX) therapy in patients with Rheumatoid Arthritis (RA) and to identify factors that promote either adherence or non adherence. METHODS One hundred Rheumatoid Arthritis patients on MTX for at least two months were enrolled. Questionnaire was completed by direct interview. Details recorded were, demographics (age, sex, education, monthly income...
متن کاملCombination second-line therapy for rheumatoid arthritis.
WHILE the treatment of RA has become more aggressive in recent years by the earlier use of second-line agents, remissions, as measured by the ACR [1], resulting from these therapies are rare. Concern has been expressed that the mortality risk in patients with RA is similar to that seen in Stage IV Hodgkin's disease or three vessel coronary artery disease [2]. Certainly, the consideration of dis...
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ژورنال
عنوان ژورنال: Arthritis Care & Research
سال: 2015
ISSN: 2151-464X,2151-4658
DOI: 10.1002/acr.22638